Basic Information | |
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Species | Aquilegia coerulea |
Cazyme ID | Aquca_001_00331.2 |
Family | GT47 |
Protein Properties | Length: 617 Molecular Weight: 70618.6 Isoelectric Point: 8.2701 |
Chromosome | Chromosome/Scaffold: 1 Start: 3472162 End: 3476455 |
Description | Exostosin family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 292 | 568 | 0 |
NMLKIYIYNEGDKPIFHHPNLKGIYASEGWFMKLLERNKQFVVKNPLEAHMFYLPFSSLVLRKTLIQPHWVLAEYLKNYVELIAGKYRFWNRTGGADHFL VACHDWALEETKKYMGTCIRALCNTDAARSFKIGKDVSLPVTYIRFEDNPVRSLGGKPPSKRPFLAFFAGSMHGHVRPILLRHWENKDPDMKIFGRLPPS EKPSYVQYMKSSKYCICAKGYEVHTPRVVEAIFHECVPVIISDNYVPPFFEVLKWETFSVFILEKDIPNLKNVLLSI |
Full Sequence |
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Protein Sequence Length: 617 Download |
MVCAPQFQKL YKIETKRLIL VVGILFPIIV VLLSSSLSLP YGDVLQSLLS FKSVMVRQSN 60 VVHNSNSTSS SMVNDTEVII NQENEIRVQD KDPNNDDQLE EEEEDQTSDF ESDKTVNETS 120 TVGSAEFEDN TKSDHSSSSL TSRNITNSEA NFVSEPLFVS SPVDAETHST ISSEFDVDLS 180 KSNVSTKTQN SSVGESATDT FPENQSSVQS HVDLVQSTKN SSMTSNNSTK AKRLGRVRPI 240 SISEMNKLLH QNRLHSHAMI ENAPIVNSGR ELYAPLYRNI SMFKRSYELM ENMLKIYIYN 300 EGDKPIFHHP NLKGIYASEG WFMKLLERNK QFVVKNPLEA HMFYLPFSSL VLRKTLIQPH 360 WVLAEYLKNY VELIAGKYRF WNRTGGADHF LVACHDWALE ETKKYMGTCI RALCNTDAAR 420 SFKIGKDVSL PVTYIRFEDN PVRSLGGKPP SKRPFLAFFA GSMHGHVRPI LLRHWENKDP 480 DMKIFGRLPP SEKPSYVQYM KSSKYCICAK GYEVHTPRVV EAIFHECVPV IISDNYVPPF 540 FEVLKWETFS VFILEKDIPN LKNVLLSIPK KKYLELQSRV KKVQKHFLWH KNPVKHDVFY 600 MTLHSIWYNR VFQISV* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 1.0e-63 | 294 | 568 | 297 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
EMBL | CBI28021.1 | 0 | 7 | 614 | 7 | 662 | unnamed protein product [Vitis vinifera] |
RefSeq | XP_002280595.1 | 0 | 7 | 614 | 5 | 660 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002281263.1 | 0 | 6 | 616 | 4 | 668 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002309547.1 | 0 | 184 | 614 | 12 | 468 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002324801.1 | 0 | 251 | 614 | 25 | 395 | predicted protein [Populus trichocarpa] |