Basic Information | |
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Species | Linum usitatissimum |
Cazyme ID | Lus10001958 |
Family | GT47 |
Protein Properties | Length: 303 Molecular Weight: 35054.7 Isoelectric Point: 9.7914 |
Chromosome | Chromosome/Scaffold: 1801 Start: 98396 End: 99393 |
Description | Exostosin family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 7 | 255 | 0 |
GRKLKTEDPWRAHAYFMPFSVTWMVKYLYTPLSYDLAPLRRFVADYVTVISSKYPFWNRTLSADNFMLASHDWVGSHASKGNQLVQDKSIRVLCNANTSE GFNPRKDVSLPEIHLYGGNIPTELLLSPQPKSHRRPYLEFFARGLHGPIRPILLSHWRNRNDPQLKVFEYLPKNVSYYSLMLKSKFCLCPSGHEVASPRI VEAIYADCVPVILSENYVLPFSDVLRWQVFSVEVHVAEIPMLKEILGSI |
Full Sequence |
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Protein Sequence Length: 303 Download |
MEHGSSGRKL KTEDPWRAHA YFMPFSVTWM VKYLYTPLSY DLAPLRRFVA DYVTVISSKY 60 PFWNRTLSAD NFMLASHDWV GSHASKGNQL VQDKSIRVLC NANTSEGFNP RKDVSLPEIH 120 LYGGNIPTEL LLSPQPKSHR RPYLEFFARG LHGPIRPILL SHWRNRNDPQ LKVFEYLPKN 180 VSYYSLMLKS KFCLCPSGHE VASPRIVEAI YADCVPVILS ENYVLPFSDV LRWQVFSVEV 240 HVAEIPMLKE ILGSIPEEEY SRLKKGVRAV RKHFVLNQPA KRFDVFHMIL HSVWLRRLDI 300 KL* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 6.0e-50 | 12 | 255 | 256 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
EMBL | CBI21064.1 | 0 | 1 | 302 | 181 | 477 | unnamed protein product [Vitis vinifera] |
RefSeq | NP_197913.4 | 0 | 9 | 302 | 189 | 479 | catalytic [Arabidopsis thaliana] |
RefSeq | XP_002285237.1 | 0 | 1 | 302 | 37 | 333 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002324871.1 | 0 | 1 | 302 | 37 | 333 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002515489.1 | 0 | 1 | 302 | 184 | 480 | catalytic, putative [Ricinus communis] |
EST Download unfiltered results here | ||||
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Hit | Length | Start | End | EValue |
DR923559 | 240 | 63 | 302 | 0 |
GO363500 | 270 | 7 | 276 | 0 |
GE475605 | 293 | 12 | 302 | 0 |
GW864815 | 284 | 9 | 292 | 0 |
DV154957 | 223 | 83 | 301 | 0 |
Sequence Alignments (This image is cropped. Click for full image.) |
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