Basic Information | |
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Species | Eucalyptus grandis |
Cazyme ID | Eucgr.L02716.1 |
Family | GT47 |
Protein Properties | Length: 476 Molecular Weight: 55117 Isoelectric Point: 8.992 |
Chromosome | Chromosome/Scaffold: 1281 Start: 3858 End: 6542 |
Description | Exostosin family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 139 | 424 | 0 |
KGFKIWTYREGDHPLVHYGPVNDLYAIEGQFIDEMEDKRNPFRASHPDQAHAFFLPFSVTNVVSYVYQPILSIHDYRRDRLQRFVRDYVHVVADRHEHWN RSKGADHFMFSCHDWAPDVSSADPELFKNFIRVLCNANTSEGFRPERDVSMADIYLAYGELGPPRLGLDPRNRSILAFFAGGAHGYIRELLLEHWKDKDA DVQVHEYLPKGQNYTQLMGRSRYCLCPSGFEVASSRIVEAIYAECVPVIIKDSYWLPFSDVLNWSKFSVRIPVNRIKDIKTILEAI |
Full Sequence |
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Protein Sequence Length: 476 Download |
MASTDFPYAQ FSLVPAICLL LLIFLCYSPF DAKLNNPIFS LSSSSTSPET NNHTGTPSVL 60 VNGPRSTLMY QSRSRHNTNK IKKSSLEKIE DDLAQVRAAI RKAIRSQSYV SDGKETFIPR 120 GNVYRNPYAF YQSHMEMMKG FKIWTYREGD HPLVHYGPVN DLYAIEGQFI DEMEDKRNPF 180 RASHPDQAHA FFLPFSVTNV VSYVYQPILS IHDYRRDRLQ RFVRDYVHVV ADRHEHWNRS 240 KGADHFMFSC HDWAPDVSSA DPELFKNFIR VLCNANTSEG FRPERDVSMA DIYLAYGELG 300 PPRLGLDPRN RSILAFFAGG AHGYIRELLL EHWKDKDADV QVHEYLPKGQ NYTQLMGRSR 360 YCLCPSGFEV ASSRIVEAIY AECVPVIIKD SYWLPFSDVL NWSKFSVRIP VNRIKDIKTI 420 LEAIPFEKYV KLQKRVVKVR RHFEVHRPAK PFDVIHMALH SVWLRRLNIK LEERD* 480 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 3.0e-62 | 137 | 424 | 306 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | ABP03872.1 | 0 | 61 | 471 | 55 | 465 | Exostosin-like [Medicago truncatula] |
GenBank | ABP03873.1 | 0 | 70 | 471 | 219 | 613 | Exostosin-like [Medicago truncatula] |
EMBL | CBI21065.1 | 0 | 82 | 471 | 11 | 400 | unnamed protein product [Vitis vinifera] |
EMBL | CBI25537.1 | 0 | 35 | 471 | 31 | 475 | unnamed protein product [Vitis vinifera] |
RefSeq | XP_002263848.1 | 0 | 83 | 471 | 4 | 394 | PREDICTED: hypothetical protein [Vitis vinifera] |