Basic Information | |
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Species | Aquilegia coerulea |
Cazyme ID | Aquca_009_00605.1 |
Family | GT47 |
Protein Properties | Length: 494 Molecular Weight: 56814.4 Isoelectric Point: 7.1281 |
Chromosome | Chromosome/Scaffold: 9 Start: 3609690 End: 3611646 |
Description | Exostosin family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 156 | 431 | 0 |
KSFKIYVYPHSKDEPYAHALLPVDFEPSGNYASESYFKKSLMQSHFITKDPSEANLFFLPFSISRLRHDPRVSVGGLQDFVRSYIYNISQKYPYWNRTSG TDHFYVACHSIGRSAMEKAEEVKFNAIQVVCSSSYFLSGYIAHKDASLPQIWPRQGDPPQVASIDRKKLAFFAGAINSPVRTKLLEVWKNDSEISVHFGR LPTPYSDELLGSKFCLHVKGFEVNTARIGDAIYYGCVPVIIANHYDLPFADILDWKSFSLVVPTLDIPLLKEILHE |
Full Sequence |
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Protein Sequence Length: 494 Download |
MVRSSSFLHN FSSIHRNLID SFNSVFFLVP LTLAFITYLY ILFYIYLTSK YFIFTHHYNP 60 TNFLPKPSNQ FVNTSSSLFH HQIIQSQPHN SSVVSSFHVS ESIQKFTSLT SSSKDGEDHA 120 LQEAKELNGS KGNSVVSEEV FHDKDMFLED YKEMNKSFKI YVYPHSKDEP YAHALLPVDF 180 EPSGNYASES YFKKSLMQSH FITKDPSEAN LFFLPFSISR LRHDPRVSVG GLQDFVRSYI 240 YNISQKYPYW NRTSGTDHFY VACHSIGRSA MEKAEEVKFN AIQVVCSSSY FLSGYIAHKD 300 ASLPQIWPRQ GDPPQVASID RKKLAFFAGA INSPVRTKLL EVWKNDSEIS VHFGRLPTPY 360 SDELLGSKFC LHVKGFEVNT ARIGDAIYYG CVPVIIANHY DLPFADILDW KSFSLVVPTL 420 DIPLLKEILH EVSSDEYTTL QGNVLKVRRH FQWNLLPTNY DAFYMVIYEL WLRRSSMRFS 480 SNEFLDLDQN SKL* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 2.0e-70 | 154 | 429 | 293 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | ABD28410.1 | 0 | 29 | 477 | 26 | 479 | Exostosin-like [Medicago truncatula] |
EMBL | CBI39073.1 | 0 | 116 | 478 | 81 | 444 | unnamed protein product [Vitis vinifera] |
RefSeq | XP_002265438.1 | 0 | 116 | 478 | 81 | 442 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002325425.1 | 0 | 154 | 480 | 1 | 323 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002525728.1 | 0 | 154 | 478 | 1 | 325 | catalytic, putative [Ricinus communis] |