Basic Information | |
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Species | Aquilegia coerulea |
Cazyme ID | Aquca_013_00915.1 |
Family | GT47 |
Protein Properties | Length: 519 Molecular Weight: 58811.4 Isoelectric Point: 9.2901 |
Chromosome | Chromosome/Scaffold: 13 Start: 6036048 End: 6038191 |
Description | Exostosin family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 185 | 468 | 0 |
EKRFRVWTYKEGEPPLVHDGPVNNIYSIEGQFIYEMDSGKNPLMAKSPDEAHVFFLPFSVANVIRYVYKPVKSFSRDRLQLLVEDYISVIANRYPYWNRS SGADHFMVACHDWAPDISGAHPELFQHFIRVLCNANASEGFQAQRDVSMPEINLPFGRLGAPNLAKPLSKRSILAFFAGGCHGHIRKILLKHWKGKDNEV QVHEYLPKGLNYTELMGQSKYCLCPSGWEVASPRIVEAIQAGCVPVILSEDYVLPFSDVLDWSQFSVRIPVEKIPEIKAILKEI |
Full Sequence |
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Protein Sequence Length: 519 Download |
MGALSCTTTF LLLPPLLLFL CFSTFDKIQL TSTTFSSQYS FPWYLENIVT TTSLSSSASS 60 ISNISNTSSS ATNITSISTS SNISSSLSQS DHHLSNEFSN ATIFTVITTT NTTYHGVSNA 120 TYLPRIREKT SSLNKLEDGL ARARAAIQTA IRRRNYTSHK KEDFIPRGPV YRNPYAFHQS 180 HIEMEKRFRV WTYKEGEPPL VHDGPVNNIY SIEGQFIYEM DSGKNPLMAK SPDEAHVFFL 240 PFSVANVIRY VYKPVKSFSR DRLQLLVEDY ISVIANRYPY WNRSSGADHF MVACHDWAPD 300 ISGAHPELFQ HFIRVLCNAN ASEGFQAQRD VSMPEINLPF GRLGAPNLAK PLSKRSILAF 360 FAGGCHGHIR KILLKHWKGK DNEVQVHEYL PKGLNYTELM GQSKYCLCPS GWEVASPRIV 420 EAIQAGCVPV ILSEDYVLPF SDVLDWSQFS VRIPVEKIPE IKAILKEIPI RKFLQLQMRV 480 MSVQKHFVVN RPAKRFDVMH MVLHSVWLRR LNFQLPIS* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 3.0e-63 | 184 | 468 | 303 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | ABP03873.1 | 0 | 126 | 515 | 230 | 613 | Exostosin-like [Medicago truncatula] |
EMBL | CBI21065.1 | 0 | 128 | 517 | 10 | 402 | unnamed protein product [Vitis vinifera] |
EMBL | CBI25537.1 | 0 | 90 | 516 | 29 | 476 | unnamed protein product [Vitis vinifera] |
RefSeq | XP_002515488.1 | 0 | 1 | 515 | 12 | 468 | catalytic, putative [Ricinus communis] |
RefSeq | XP_002531945.1 | 0 | 127 | 518 | 70 | 453 | catalytic, putative [Ricinus communis] |