Basic Information | |
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Species | Gossypium raimondii |
Cazyme ID | Gorai.010G107300.2 |
Family | GT47 |
Protein Properties | Length: 645 Molecular Weight: 73626.2 Isoelectric Point: 5.668 |
Chromosome | Chromosome/Scaffold: 10 Start: 19851999 End: 19856313 |
Description | Exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 313 | 594 | 0 |
STLKVYIYKEGKKPIFHKPVLKGIYASEGWFMKQLQANRNFVTKKPREAQLFYLPFSSRMLEETLYVPDSHSIQNLVEYLKNYADTIAAKYPYWNRTQGA DHFLVACHDWATSETKEYMANCIRALCNSDIREGYIFGKDVSLPETTIRNPQRPLRDLGGEPPSKRSILAFFAGGMHGYLRPILLQQWGNKDPDMKIFGT MHNGKGKLNYAQHMKRSKYCICPRGYEVNSPRVVEAIFYECVPVIISDNFIPPFFEVLNWESLAVFVLEKDIPNLKKILLSI |
Full Sequence |
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Protein Sequence Length: 645 Download |
MGHDLKSWFQ LDARKLIWLI CAIMVIITFQ YLELSSENVL SAVVPSGKIS VEGQSSFLAS 60 APSSTEPDGT IRYVTHSIGL EYNGTYAGSE TVHGNEVSEE RDMDSNDDVI SETDVDLNKS 120 STFEEGSESP KESLSEELVD LIKNSTVYDA ESSKNMTTAE VEGGLSLELS KENNMATLDS 180 LNQTSAVNEA TNDFGTYEVN DKDQNSDSIL DNDNNSGRKS SSEEFEDYPE SYNNKTVAKE 240 APTTIADMNN LLYRSRVSYH STTPRWASAA DKVLLNVRSQ IEKAPILEND QQLYAPLYRN 300 VSMFKRSYEL MESTLKVYIY KEGKKPIFHK PVLKGIYASE GWFMKQLQAN RNFVTKKPRE 360 AQLFYLPFSS RMLEETLYVP DSHSIQNLVE YLKNYADTIA AKYPYWNRTQ GADHFLVACH 420 DWATSETKEY MANCIRALCN SDIREGYIFG KDVSLPETTI RNPQRPLRDL GGEPPSKRSI 480 LAFFAGGMHG YLRPILLQQW GNKDPDMKIF GTMHNGKGKL NYAQHMKRSK YCICPRGYEV 540 NSPRVVEAIF YECVPVIISD NFIPPFFEVL NWESLAVFVL EKDIPNLKKI LLSIPDERYR 600 QMQLSVKKAQ QHFLWHPRPV KYDIFHMILH SVWYNRVLQM EKPR* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 9.0e-73 | 311 | 594 | 304 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
RefSeq | NP_195005.1 | 0 | 237 | 640 | 189 | 593 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | XP_002281263.1 | 0 | 1 | 640 | 1 | 666 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002309547.1 | 0 | 203 | 644 | 22 | 471 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002324801.1 | 0 | 248 | 644 | 1 | 398 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002514248.1 | 0 | 243 | 644 | 275 | 676 | catalytic, putative [Ricinus communis] |