| Basic Information | |
|---|---|
| Species | Linum usitatissimum |
| Cazyme ID | Lus10035437 |
| Family | CE1 |
| Protein Properties | Length: 270 Molecular Weight: 30256.4 Isoelectric Point: 7.3037 |
| Chromosome | Chromosome/Scaffold: 151 Start: 971833 End: 973991 |
| Description | S-formylglutathione hydrolase |
| View CDS | |
| External Links |
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| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
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| Family | Start | End | Evalue |
| CE1 | 25 | 266 | 0 |
| SSTLGCSMNFHVYFPPSSSPSQKFPVLYWLSGLTCTDENFIVKAGAQPLAAAEGVALIAPDTSPSAGFYLNATQEKWKNWKMYDYIVKELPTLLTENFPQ LDTSRASIFGHSMGGHGALTIYLKNLDKYKSVSAFAPISNPMNCPWGQKAFTNYLGSNKADWEKYDATCLVSKSHDVSATILIDQGEDDKFLHDKQLLVD KFEEACRSVNVPVLLRRQPGYDHSFFFIATFIDDHIRHHVQA | |||
| Full Sequence |
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| Protein Sequence Length: 270 Download |
| METKPSEISS TKMFGGYNKR FKHFSSTLGC SMNFHVYFPP SSSPSQKFPV LYWLSGLTCT 60 DENFIVKAGA QPLAAAEGVA LIAPDTSPSA GFYLNATQEK WKNWKMYDYI VKELPTLLTE 120 NFPQLDTSRA SIFGHSMGGH GALTIYLKNL DKYKSVSAFA PISNPMNCPW GQKAFTNYLG 180 SNKADWEKYD ATCLVSKSHD VSATILIDQG EDDKFLHDKQ LLVDKFEEAC RSVNVPVLLR 240 RQPGYDHSFF FIATFIDDHI RHHVQALNL* |
| Functional Domains Download unfiltered results here | ||||||||
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| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| COG1506 | DAP2 | 2.0e-7 | 24 | 249 | 238 | + Dipeptidyl aminopeptidases/acylaminoacyl-peptidases [Amino acid transport and metabolism] | ||
| pfam00756 | Esterase | 9.0e-51 | 25 | 262 | 259 | + Putative esterase. This family contains Esterase D. However it is not clear if all members of the family have the same function. This family is related to the pfam00135 family. | ||
| COG0627 | COG0627 | 6.0e-76 | 1 | 269 | 312 | + Predicted esterase [General function prediction only] | ||
| TIGR02821 | fghA_ester_D | 2.0e-116 | 8 | 267 | 277 | + S-formylglutathione hydrolase. This model describes a protein family from bacteria, yeast, and human, with a conserved critical role in formaldehyde detoxification as S-formylglutathione hydrolase (EC 3.1.2.12). Members in eukaryotes such as the human protein are better known as esterase D (EC 3.1.1.1), an enzyme with broad specificity, although S-formylglutathione hydrolase has now been demonstrated as well [Cellular processes, Detoxification]. | ||
| PLN02442 | PLN02442 | 0 | 1 | 269 | 285 | + S-formylglutathione hydrolase | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0004091 | carboxylesterase activity |
| GO:0006508 | proteolysis |
| GO:0008236 | serine-type peptidase activity |
| GO:0016023 | cytoplasmic membrane-bounded vesicle |
| GO:0016787 | hydrolase activity |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | ACJ11734.1 | 0 | 1 | 269 | 1 | 284 | S-formylglutathione hydrolase [Gossypium hirsutum] |
| GenBank | ACU19052.1 | 0 | 1 | 269 | 1 | 284 | unknown [Glycine max] |
| RefSeq | XP_002284489.1 | 0 | 1 | 269 | 1 | 284 | PREDICTED: hypothetical protein isoform 1 [Vitis vinifera] |
| RefSeq | XP_002284491.1 | 0 | 1 | 269 | 1 | 268 | PREDICTED: hypothetical protein isoform 2 [Vitis vinifera] |
| RefSeq | XP_002308013.1 | 0 | 1 | 255 | 1 | 270 | esterase d, s-formylglutathione hydrolase [Populus trichocarpa] |
| Annotations - PDB Download unfiltered results here | |||||||
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| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 3fcx_B | 0 | 7 | 268 | 5 | 281 | A Chain A, Crystal Structure Of Human Esterase D |
| PDB | 3fcx_A | 0 | 7 | 268 | 5 | 281 | A Chain A, Crystal Structure Of Human Esterase D |
| PDB | 3s8y_A | 0 | 8 | 268 | 7 | 279 | A Chain A, Bromide Soaked Structure Of An Esterase From The Oil-Degrading Bacterium Oleispira Antarctica |
| PDB | 3i6y_B | 0 | 8 | 268 | 7 | 279 | A Chain A, Structure Of An Esterase From The Oil-Degrading Bacterium Oleispira Antarctica |
| PDB | 3i6y_A | 0 | 8 | 268 | 7 | 279 | A Chain A, Structure Of An Esterase From The Oil-Degrading Bacterium Oleispira Antarctica |
| Hydropathy |
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| EST Download unfiltered results here | ||||
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| Hit | Length | Start | End | EValue |
| DT549152 | 283 | 1 | 267 | 0 |
| ES807790 | 286 | 1 | 270 | 0 |
| ES841762 | 281 | 1 | 265 | 0 |
| DV157903 | 286 | 1 | 270 | 0 |
| DT490294 | 286 | 1 | 270 | 0 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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| Phylogeny |
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