| Basic Information | |
|---|---|
| Species | Malus domestica |
| Cazyme ID | MDP0000278182 |
| Family | GT1 |
| Protein Properties | Length: 633 Molecular Weight: 69763.1 Isoelectric Point: 6.6147 |
| Chromosome | Chromosome/Scaffold: 006361339 Start: 325 End: 4968 |
| Description | UDP-Glycosyltransferase superfamily protein |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
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| Family | Start | End | Evalue |
| GT1 | 194 | 604 | 0 |
| IVGTRGDVQPFVAIGKRLQEYGHRVRLATHANFKDFVLTAGLEFYPLGGDPKVLAGYMVKNKGFLPSGPSEISIQRQQLREIIFSLLPACKEPDPDSKVP FKAEAIIANPPAYGHSHXAEALKVPLHIFFTMPWTPTXEFPHPLSRVTQPIGYRLSYQIVDALIXLGIRDMINEFRKKMLKLRPITYLSGNYSSQPDVPH GYIWSPHLVPKPKDWGPXIDVVGFCFLDLASNYEPPEPLAKWLEAGDEPVYIGFGSLPLQEPEKMTDIILQALEITXQRGIINRGWGGLGNSVEPXDSVY LVDNCPHDWLFKRCSAVVHHGGAGTTAAGLKAACPTTIIPFFGDQPFWGERVHARGVGPAPIPVEEFSLDKLVDAIRFMLDPKVKECAIEIAKAMDNEDG VRGAVKAFHRH | |||
| Full Sequence |
|---|
| Protein Sequence Length: 633 Download |
| MESSADDRRS HSGSSSDMSV SFEAEVPRNP NDEYATPSSG SVVAFLVFFF IGIVFFVTLV 60 SNLWKNADFV GKLERDVQTE RNSGESSSAV RTSSGSSQLT ASARLSQNQA LSVTLAKLFD 120 QRTPFRKKRK YIKQLATVKD DGTVQFDVPG DIKPQYLDFG TGAAHSEAAS GAEACGETEA 180 EVRDIPPLQI VMLIVGTRGD VQPFVAIGKR LQEYGHRVRL ATHANFKDFV LTAGLEFYPL 240 GGDPKVLAGY MVKNKGFLPS GPSEISIQRQ QLREIIFSLL PACKEPDPDS KVPFKAEAII 300 ANPPAYGHSH XAEALKVPLH IFFTMPWTPT XEFPHPLSRV TQPIGYRLSY QIVDALIXLG 360 IRDMINEFRK KMLKLRPITY LSGNYSSQPD VPHGYIWSPH LVPKPKDWGP XIDVVGFCFL 420 DLASNYEPPE PLAKWLEAGD EPVYIGFGSL PLQEPEKMTD IILQALEITX QRGIINRGWG 480 GLGNSVEPXD SVYLVDNCPH DWLFKRCSAV VHHGGAGTTA AGLKAACPTT IIPFFGDQPF 540 WGERVHARGV GPAPIPVEEF SLDKLVDAIR FMLDPKVKEC AIEIAKAMDN EDGVRGAVKA 600 FHRHFPCNRS DDGEPDQSLP ARKGLLSIRR CFG |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
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| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| COG1819 | COG1819 | 7.0e-31 | 190 | 603 | 423 | + Glycosyl transferases, related to UDP-glucuronosyltransferase [Carbohydrate transport and metabolism / Signal transduction mechanisms] | ||
| pfam03033 | Glyco_transf_28 | 2.0e-32 | 190 | 334 | 145 | + Glycosyltransferase family 28 N-terminal domain. The glycosyltransferase family 28 includes monogalactosyldiacylglycerol synthase (EC 2.4.1.46) and UDP-N-acetylglucosamine transferase (EC 2.4.1.-). This N-terminal domain contains the acceptor binding site and likely membrane association site. This family also contains a large number of proteins that probably have quite distinct activities. | ||
| cd03784 | GT1_Gtf_like | 1.0e-118 | 190 | 604 | 419 | + This family includes the Gtfs, a group of homologous glycosyltransferases involved in the final stages of the biosynthesis of antibiotics vancomycin and related chloroeremomycin. Gtfs transfer sugar moieties from an activated NDP-sugar donor to the oxidatively cross-linked heptapeptide core of vancomycin group antibiotics. The core structure is important for the bioactivity of the antibiotics. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0005975 | carbohydrate metabolic process |
| GO:0008152 | metabolic process |
| GO:0016758 | transferase activity, transferring hexosyl groups |
| GO:0030259 | lipid glycosylation |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| DDBJ | BAC22617.1 | 0 | 107 | 633 | 83 | 600 | UDP-glucose:sterol 3-O-glucosyltransferase [Panax ginseng] |
| EMBL | CBI37267.1 | 0 | 116 | 633 | 103 | 613 | unnamed protein product [Vitis vinifera] |
| RefSeq | XP_002265023.1 | 0 | 116 | 633 | 150 | 660 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002512608.1 | 0 | 85 | 633 | 51 | 594 | transferase, transferring glycosyl groups, putative [Ricinus communis] |
| RefSeq | XP_002521125.1 | 0 | 92 | 633 | 88 | 624 | transferase, transferring glycosyl groups, putative [Ricinus communis] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 3h4t_A | 5e-30 | 188 | 623 | 1 | 392 | A Chain A, Lip5(mit)2 |
| PDB | 3h4i_A | 5e-30 | 188 | 623 | 1 | 392 | A Chain A, Chimeric Glycosyltransferase For The Generation Of Novel Natural Products |
| PDB | 1rrv_B | 4e-21 | 188 | 585 | 1 | 380 | A Chain A, X-Ray Crystal Structure Of Tdp-Vancosaminyltransferase Gtfd As A Complex With Tdp And The Natural Substrate, Desvancosaminyl Vancomycin. |
| PDB | 1rrv_A | 4e-21 | 188 | 585 | 1 | 380 | A Chain A, X-Ray Crystal Structure Of Tdp-Vancosaminyltransferase Gtfd As A Complex With Tdp And The Natural Substrate, Desvancosaminyl Vancomycin. |
| PDB | 1iir_A | 7e-20 | 432 | 591 | 230 | 385 | A Chain A, Crystal Structure Of Udp-Glucosyltransferase Gtfb |
