Basic Information | |
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Species | Malus domestica |
Cazyme ID | MDP0000118748 |
Family | GH19 |
Protein Properties | Length: 287 Molecular Weight: 31587.8 Isoelectric Point: 8.0377 |
Chromosome | Chromosome/Scaffold: 000045372 Start: 2295 End: 3517 |
Description | Chitinase family protein |
View CDS |
External Links |
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NCBI Taxonomy |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GH19 | 47 | 281 | 0 |
SSLISKKLFHTLFLHKDDMACPAKDFYTYHSFIKASKSFPGFGTTGSLTTRKSEIAAFLAQISHETTGGWATAPDGPYAWGLCFKEEISPPSDYCDSNNK EWPCYPGKSYKGRGPIQLSWNYNYGPAGKALGFDGLKNPEVVANNSMIALKTALWFWMTEQKPKPSSHDVMVGLYVPTEADVAANRTVGYGLVTNIINGR LECGIPNDARVNDRIGYFRRYAGLLNVDTGPNLDC |
Full Sequence |
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Protein Sequence Length: 287 Download |
MALPSFNLST SFFLVSFAFF SIAINLFSTS NAPSRAEAAR SDCLPISSLI SKKLFHTLFL 60 HKDDMACPAK DFYTYHSFIK ASKSFPGFGT TGSLTTRKSE IAAFLAQISH ETTGGWATAP 120 DGPYAWGLCF KEEISPPSDY CDSNNKEWPC YPGKSYKGRG PIQLSWNYNY GPAGKALGFD 180 GLKNPEVVAN NSMIALKTAL WFWMTEQKPK PSSHDVMVGL YVPTEADVAA NRTVGYGLVT 240 NIINGRLECG IPNDARVNDR IGYFRRYAGL LNVDTGPNLD CENQKSF |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
COG3179 | COG3179 | 7.0e-7 | 96 | 205 | 129 | + Predicted chitinase [General function prediction only] | ||
cd00442 | lysozyme_like | 3.0e-13 | 102 | 215 | 114 | + lysozyme_like domain. This contains several members including Soluble Lytic Transglycosylases (SLT), Goose Egg-White Lysozymes (GEWL), Hen Egg-White Lysozymes (HEWL), chitinases, bacteriophage lambda lysozymes, endolysins, autolysins, and chitosanases. All the members are involved in the hydrolysis of beta-1,4- linked polysaccharides. | ||
pfam00182 | Glyco_hydro_19 | 7.0e-128 | 49 | 281 | 233 | + Chitinase class I. | ||
cd00325 | chitinase_glyco_hydro_19 | 3.0e-133 | 50 | 281 | 232 | + Glycoside hydrolase family 19 chitinase domain. Chitinases are enzymes that catalyze the hydrolysis of the beta-1,4-N-acetyl-D-glucosamine linkages in chitin polymers. Family 19 chitinases are found primarily in plants (classes I, III, and IV), but some are found in bacteria. Class I and II chitinases are similar in their catalytic domains. Class I chitinases have an N-terminal cysteine-rich, chitin-binding domain which is separated from the catalytic domain by a proline and glycine-rich hinge region. Class II chitinases lack both the chitin-binding domain and the hinge region. Class IV chitinases are similar to class I chitinases but they are smaller in size due to certain deletions. Despite any significant sequence homology with lysozymes, structural analysis reveals that family 19 chitinases, together with family 46 chitosanases, are similar to several lysozymes including those from T4-phage and from goose. The structures reveal that the different enzyme groups arose from a common ancestor glycohydrolase antecedent to the procaryotic/eucaryotic divergence. |
Gene Ontology | |
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GO Term | Description |
GO:0004568 | chitinase activity |
GO:0006032 | chitin catabolic process |
GO:0016998 | cell wall macromolecule catabolic process |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | AAF00131.1 | 0 | 45 | 287 | 35 | 277 | AF147091_1 class II chitinase [Fragaria x ananassa] |
GenBank | ABU55294.1 | 0 | 45 | 287 | 35 | 277 | class II chitinase [Fragaria x ananassa] |
GenBank | ACU24402.1 | 0 | 36 | 287 | 21 | 272 | unknown [Glycine max] |
EMBL | CAA57773.1 | 0 | 36 | 287 | 26 | 277 | chitinase (class II) [Arachis hypogaea] |
RefSeq | XP_002515175.1 | 0 | 13 | 287 | 8 | 274 | class I chitinase, putative [Ricinus communis] |
Annotations - PDB Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
PDB | 3cql_B | 0 | 46 | 287 | 2 | 242 | A Chain A, Crystal Structure Of Gh Family 19 Chitinase From Carica Papaya |
PDB | 3cql_A | 0 | 46 | 287 | 2 | 242 | A Chain A, Crystal Structure Of Gh Family 19 Chitinase From Carica Papaya |
PDB | 4dyg_B | 0 | 44 | 287 | 1 | 243 | A Chain A, Crystal Structure Of Gh Family 19 Chitinase From Carica Papaya |
PDB | 4dyg_A | 0 | 44 | 287 | 1 | 243 | A Chain A, Crystal Structure Of Gh Family 19 Chitinase From Carica Papaya |
PDB | 4dwx_B | 0 | 44 | 287 | 1 | 243 | A Chain A, Crystal Structure Of A Family Gh-19 Chitinase From Rye Seeds |