Basic Information | |
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Species | Malus domestica |
Cazyme ID | MDP0000799020 |
Family | GT20 |
Protein Properties | Length: 863 Molecular Weight: 97518.5 Isoelectric Point: 6.1934 |
Chromosome | Chromosome/Scaffold: 001735269 Start: 10205 End: 12988 |
Description | trehalose-phosphatase/synthase 9 |
View CDS |
External Links |
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NCBI Taxonomy |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT20 | 59 | 547 | 0 |
CEKKIIVANFLPLHXQKDAKSGKWCFSFDEDALSLQLKDGFPSGTVVIYVGSLKVDVEASEQEEVSQKLLEEFNCVPTFLPSELHKKYYHGFCKQYLWPL FHYMLPMYPDLSSRFDRQLWQAYVSANKKYADKVMEVINPEDDCVWVHDYHLMLLPTFLRRRFTRVKLGFFLHSPFPTSEIYRTLPVRDEILRALLNVDL IGFHTFDYARHFLSCCSRMLGLEYESKRGYIGLEYFGRTVYIKILAAGIHMGQLESALNHPSSSMKAKEIQEQFKGKKIIVGVDDMDIFKGISLKLMAME QLLMQHLEMRGKVVLVQIVNPARSTGKDVQEAKKETYSMTRRINQVFGFPGYEPVVLIDRSLPFHEKAAYYSLAECCIVNAVRDGMNLVPYEYIICRQGN QNIDKAVGVASDSPRTSTLVVSEFIGCSPSLSGAIRVNPWNIEAAADALNEALTMPDLEKQLRHEKHFRYVSSHDVAYWSRSFLQDLER |
Full Sequence |
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Protein Sequence Length: 863 Download |
MLSRSCLSLL ELSSGDMLNF PQTPRNLPRV MTLQGVIPDA ESSDGINNED INVPPSEVCE 60 KKIIVANFLP LHXQKDAKSG KWCFSFDEDA LSLQLKDGFP SGTVVIYVGS LKVDVEASEQ 120 EEVSQKLLEE FNCVPTFLPS ELHKKYYHGF CKQYLWPLFH YMLPMYPDLS SRFDRQLWQA 180 YVSANKKYAD KVMEVINPED DCVWVHDYHL MLLPTFLRRR FTRVKLGFFL HSPFPTSEIY 240 RTLPVRDEIL RALLNVDLIG FHTFDYARHF LSCCSRMLGL EYESKRGYIG LEYFGRTVYI 300 KILAAGIHMG QLESALNHPS SSMKAKEIQE QFKGKKIIVG VDDMDIFKGI SLKLMAMEQL 360 LMQHLEMRGK VVLVQIVNPA RSTGKDVQEA KKETYSMTRR INQVFGFPGY EPVVLIDRSL 420 PFHEKAAYYS LAECCIVNAV RDGMNLVPYE YIICRQGNQN IDKAVGVASD SPRTSTLVVS 480 EFIGCSPSLS GAIRVNPWNI EAAADALNEA LTMPDLEKQL RHEKHFRYVS SHDVAYWSRS 540 FLQDLERACK DHYRKRCWGI GFGLNFRILS LSPSFRKLSI DHILSVYKRT NRRAIFLDYD 600 GTIMPESSIV KTPSSEVISV LKNLCSDPKN TVFIVSGRGQ SSLSEWFAQC ENLGIAAEHG 660 YFIRWSSASS WETCSLAIDL DWKQIAEPVM KLYTEATDGS YIETKESALV WHHLDADPDF 720 GSCQAMEMLD HLENVLANEP VVVKKGQHIV EVKPQGVTKG IVAQKVLSMM IGNGNAPDFV 780 LCIGDDRSDE DMFESISSTT YSSSQAAAPE IFACTVGQKP SKARYYLDDT ADVITLLNGL 840 ATDSSLRARS NWEIQVPFEN II* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
PLN03063 | PLN03063 | 2.0e-165 | 63 | 842 | 820 | + alpha,alpha-trehalose-phosphate synthase (UDP-forming); Provisional | ||
PLN02205 | PLN02205 | 0 | 15 | 844 | 837 | + alpha,alpha-trehalose-phosphate synthase [UDP-forming] | ||
pfam00982 | Glyco_transf_20 | 0 | 60 | 547 | 492 | + Glycosyltransferase family 20. Members of this family belong to glycosyl transferase family 20. OtsA (Trehalose-6-phosphate synthase) is homologous to regions in the subunits of yeast trehalose-6-phosphate synthase/phosphate complex. | ||
PRK14501 | PRK14501 | 0 | 63 | 841 | 793 | + putative bifunctional trehalose-6-phosphate synthase/HAD hydrolase subfamily IIB; Provisional | ||
cd03788 | GT1_TPS | 0 | 63 | 546 | 485 | + Trehalose-6-Phosphate Synthase (TPS) is a glycosyltransferase that catalyses the synthesis of alpha,alpha-1,1-trehalose-6-phosphate from glucose-6-phosphate using a UDP-glucose donor. It is a key enzyme in the trehalose synthesis pathway. Trehalose is a nonreducing disaccharide present in a wide variety of organisms and may serve as a source of energy and carbon. It is characterized most notably in insect, plant, and microbial cells. Its production is often associated with a variety of stress conditions, including desiccation, dehydration, heat, cold, and oxidation. This family represents the catalytic domain of the TPS. Some members of this domain family coexist with a C-terminal trehalose phosphatase domain. |
Gene Ontology | |
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GO Term | Description |
GO:0003824 | catalytic activity |
GO:0005992 | trehalose biosynthetic process |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
EMBL | CAN78769.1 | 0 | 1 | 862 | 1 | 857 | hypothetical protein [Vitis vinifera] |
RefSeq | XP_002283215.1 | 0 | 1 | 861 | 1 | 861 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002318643.1 | 0 | 1 | 862 | 1 | 857 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002322159.1 | 0 | 1 | 862 | 1 | 861 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002511428.1 | 0 | 1 | 860 | 1 | 859 | trehalose-6-phosphate synthase, putative [Ricinus communis] |
Annotations - PDB Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
PDB | 1gz5_D | 0 | 145 | 547 | 74 | 452 | A Chain A, Trehalose-6-Phosphate Synthase. Otsa |
PDB | 1gz5_C | 0 | 145 | 547 | 74 | 452 | A Chain A, Trehalose-6-Phosphate Synthase. Otsa |
PDB | 1gz5_B | 0 | 145 | 547 | 74 | 452 | A Chain A, Trehalose-6-Phosphate Synthase. Otsa |
PDB | 1gz5_A | 0 | 145 | 547 | 74 | 452 | A Chain A, Trehalose-6-Phosphate Synthase. Otsa |
PDB | 2wtx_D | 0 | 145 | 547 | 75 | 453 | A Chain A, Insight Into The Mechanism Of Enzymatic Glycosyltransfer With Retention Through The Synthesis And Analysis Of Bisubstrate Glycomimetics Of Trehalose-6-Phosphate Synthase |
EST Download unfiltered results here | ||||
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Hit | Length | Start | End | EValue |
HO777775 | 764 | 82 | 841 | 0 |
HO779327 | 523 | 92 | 614 | 0 |
HO779327 | 253 | 611 | 863 | 0 |
HO797286 | 467 | 378 | 844 | 0 |
HO795511 | 470 | 375 | 844 | 0 |
Sequence Alignments (This image is cropped. Click for full image.) |
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