Basic Information | |
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Species | Malus domestica |
Cazyme ID | MDP0000856196 |
Family | GT20 |
Protein Properties | Length: 855 Molecular Weight: 97162.5 Isoelectric Point: 5.9988 |
Chromosome | Chromosome/Scaffold: 015983258 Start: 1232 End: 4085 |
Description | trehalose-phosphatase/synthase 7 |
View CDS |
External Links |
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NCBI Taxonomy |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT20 | 54 | 543 | 0 |
SIASDRVIIVANQLPVKAKRREDNKGWTFSWNEDSLLLQLKDGLPEDMEVLYVGSLKVSVDPKEQDDVSQVLLERFKCVPTFLPPDILSKFYDGFCKRHL WPLFHYMLPFSADQGGRFDRSLWEAYISANKLFFQRVVELINPDEDYIWIHDYHLMVLPTFLRRRFNRVRMGFFLHSPFPSSEIYRTLPVREEILKALLN ADIIGFHTFDYARHFLTCCSRMLGLVYQSKRGYLGLEYYGRNIRIKIMPVGVHMGWIESVMKVADDESRVRELTQQFEGKTMLLGIDDMDIFKGINLKIL AMEQMLKQHPNWQGKAVLVQILNPVRGKGIDLEEIRAEIQEXCRRINAEFGQPGYEPIIIIDRPVSINEKICYYNIAECVVVTAVRDGMNXTPYEYVVCR QGISGSNSCSNFGGPKKSMLVVSEFIGCSPSLSGAIRVNPWNVETTGEALNVAISVLDSEKELRHEKHYRYVSTHDVAYWSRSFLQDMQR |
Full Sequence |
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Protein Sequence Length: 855 Download |
MSQSYINLLD LASGNFPTME GKRRRFPRVN TAPGNLSDLD DDQARSVSSD QPSSIASDRV 60 IIVANQLPVK AKRREDNKGW TFSWNEDSLL LQLKDGLPED MEVLYVGSLK VSVDPKEQDD 120 VSQVLLERFK CVPTFLPPDI LSKFYDGFCK RHLWPLFHYM LPFSADQGGR FDRSLWEAYI 180 SANKLFFQRV VELINPDEDY IWIHDYHLMV LPTFLRRRFN RVRMGFFLHS PFPSSEIYRT 240 LPVREEILKA LLNADIIGFH TFDYARHFLT CCSRMLGLVY QSKRGYLGLE YYGRNIRIKI 300 MPVGVHMGWI ESVMKVADDE SRVRELTQQF EGKTMLLGID DMDIFKGINL KILAMEQMLK 360 QHPNWQGKAV LVQILNPVRG KGIDLEEIRA EIQEXCRRIN AEFGQPGYEP IIIIDRPVSI 420 NEKICYYNIA ECVVVTAVRD GMNXTPYEYV VCRQGISGSN SCSNFGGPKK SMLVVSEFIG 480 CSPSLSGAIR VNPWNVETTG EALNVAISVL DSEKELRHEK HYRYVSTHDV AYWSRSFLQD 540 MQRACADHFK RRCWGIGFGF GFRVVALDPN FRKLSIDAIV SAYRGAQNRA ILLDYDGTVM 600 PQNSIDKSPS QKVISIMNTL CVDPKNTVFI VTGRGRECLS KWFSPCQRMG IAAEHGYFLR 660 WSQNQEWETC LQGFEFGWMK TVEPVMQLYT EATDGSSIER KESALVWQYR DADPGFGSSQ 720 AKEMLDHLES VLANEPVAVK NGQFIVEVKP QGVSKGHVAE KIFSSMAENG KHADFVLCIG 780 DDRSDEDMFE IFGNSMQKKV LSPNPSVFAC TVGQKPSKAT YYLDDTAEVT NMLESLSEAF 840 ESLPPTEEGY ESSP* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
PLN03063 | PLN03063 | 5.0e-170 | 59 | 839 | 824 | + alpha,alpha-trehalose-phosphate synthase (UDP-forming); Provisional | ||
PLN02205 | PLN02205 | 0 | 1 | 845 | 852 | + alpha,alpha-trehalose-phosphate synthase [UDP-forming] | ||
pfam00982 | Glyco_transf_20 | 0 | 59 | 543 | 489 | + Glycosyltransferase family 20. Members of this family belong to glycosyl transferase family 20. OtsA (Trehalose-6-phosphate synthase) is homologous to regions in the subunits of yeast trehalose-6-phosphate synthase/phosphate complex. | ||
PRK14501 | PRK14501 | 0 | 59 | 839 | 790 | + putative bifunctional trehalose-6-phosphate synthase/HAD hydrolase subfamily IIB; Provisional | ||
cd03788 | GT1_TPS | 0 | 59 | 542 | 484 | + Trehalose-6-Phosphate Synthase (TPS) is a glycosyltransferase that catalyses the synthesis of alpha,alpha-1,1-trehalose-6-phosphate from glucose-6-phosphate using a UDP-glucose donor. It is a key enzyme in the trehalose synthesis pathway. Trehalose is a nonreducing disaccharide present in a wide variety of organisms and may serve as a source of energy and carbon. It is characterized most notably in insect, plant, and microbial cells. Its production is often associated with a variety of stress conditions, including desiccation, dehydration, heat, cold, and oxidation. This family represents the catalytic domain of the TPS. Some members of this domain family coexist with a C-terminal trehalose phosphatase domain. |
Gene Ontology | |
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GO Term | Description |
GO:0003824 | catalytic activity |
GO:0005992 | trehalose biosynthetic process |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
EMBL | CAN67058.1 | 0 | 1 | 848 | 2 | 849 | hypothetical protein [Vitis vinifera] |
RefSeq | NP_172129.1 | 0 | 1 | 842 | 2 | 839 | ATTPS7; alpha,alpha-trehalose-phosphate synthase (UDP-forming)/ transferase, transferring glycosyl groups / trehalose-phosphatase [Arabidopsis thaliana] |
RefSeq | XP_002268174.1 | 0 | 1 | 854 | 2 | 853 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002305726.1 | 0 | 1 | 844 | 2 | 843 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002522255.1 | 0 | 1 | 839 | 2 | 842 | trehalose-6-phosphate synthase, putative [Ricinus communis] |
Annotations - PDB Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
PDB | 2wtx_D | 0 | 141 | 543 | 73 | 453 | A Chain A, Insight Into The Mechanism Of Enzymatic Glycosyltransfer With Retention Through The Synthesis And Analysis Of Bisubstrate Glycomimetics Of Trehalose-6-Phosphate Synthase |
PDB | 2wtx_C | 0 | 141 | 543 | 73 | 453 | A Chain A, Insight Into The Mechanism Of Enzymatic Glycosyltransfer With Retention Through The Synthesis And Analysis Of Bisubstrate Glycomimetics Of Trehalose-6-Phosphate Synthase |
PDB | 2wtx_B | 0 | 141 | 543 | 73 | 453 | A Chain A, Insight Into The Mechanism Of Enzymatic Glycosyltransfer With Retention Through The Synthesis And Analysis Of Bisubstrate Glycomimetics Of Trehalose-6-Phosphate Synthase |
PDB | 2wtx_A | 0 | 141 | 543 | 73 | 453 | A Chain A, Insight Into The Mechanism Of Enzymatic Glycosyltransfer With Retention Through The Synthesis And Analysis Of Bisubstrate Glycomimetics Of Trehalose-6-Phosphate Synthase |
PDB | 1gz5_D | 0 | 141 | 543 | 72 | 452 | A Chain A, Trehalose-6-Phosphate Synthase. Otsa |
EST Download unfiltered results here | ||||
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Hit | Length | Start | End | EValue |
HO777775 | 770 | 80 | 843 | 0 |
HO779327 | 515 | 100 | 612 | 0 |
HO779327 | 239 | 606 | 844 | 0 |
HO795511 | 481 | 373 | 853 | 0 |
HO777775 | 77 | 1 | 76 | 0.0003 |
Sequence Alignments (This image is cropped. Click for full image.) |
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