| Basic Information | |
|---|---|
| Species | Oryza sativa |
| Cazyme ID | LOC_Os08g31030.1 |
| Family | AA3 |
| Protein Properties | Length: 585 Molecular Weight: 64103 Isoelectric Point: 9.2686 |
| Chromosome | Chromosome/Scaffold: 8 Start: 19157179 End: 19161852 |
| Description | Glucose-methanol-choline (GMC) oxidoreductase family protein |
| View CDS | |
| External Links |
|---|
| NCBI Taxonomy |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| AA3 | 45 | 575 | 0 |
| IQHEAYDYIIVGGGTAGCPLAATLSQKYKVLLLERGGSPYGNRNISHLENFHICLADDSPNSPSQGFISTDGVINARAKVLGGGTSVNAGFYSRADPSFV QDAGWDAELVNQSYPWIEERIVYWPNITPWQAALRDGLLEAGVSPYNGYSYDHLFGTKVGGTIFDEAGYRHTAADLLAAGNHNNLRVLLHASVTRIIFNT EQEHRKPRTIGVEFKDENGGQQHAFLTRNRDSEIIISAGAIGSPQLLLLSGIGPRKELKKHNISVVLRNEHVGKGMSDNPMNSIFIPTKDAPKQSLIQTV GITDGGAFIEASSGFSQSPDSIQCHHGIMSAEIGQLSTIPPKQRNLDAVKKYVHKKYNLPKEVFSGGFILSKIDGPLSTGNLVLVDTDINSNPTVTFNYF QHPKDLSRCVYGIKTIERILKTNHFTNFTLNGGGYPMEVVLNMSVTANINLIPKHTNDSTSMEQFCRDTVVTIWHYHGGCHVGKVVDQQYRVIGVSGLRV IDGSTLFRSPGTNPQATVMMMGRYMGVKILR | |||
| Full Sequence |
|---|
| Protein Sequence Length: 585 Download |
| MGLINRGVFF KILAFLCFIR SSQGRNHFTT LDLPPLLKAS SFSRIQHEAY DYIIVGGGTA 60 GCPLAATLSQ KYKVLLLERG GSPYGNRNIS HLENFHICLA DDSPNSPSQG FISTDGVINA 120 RAKVLGGGTS VNAGFYSRAD PSFVQDAGWD AELVNQSYPW IEERIVYWPN ITPWQAALRD 180 GLLEAGVSPY NGYSYDHLFG TKVGGTIFDE AGYRHTAADL LAAGNHNNLR VLLHASVTRI 240 IFNTEQEHRK PRTIGVEFKD ENGGQQHAFL TRNRDSEIII SAGAIGSPQL LLLSGIGPRK 300 ELKKHNISVV LRNEHVGKGM SDNPMNSIFI PTKDAPKQSL IQTVGITDGG AFIEASSGFS 360 QSPDSIQCHH GIMSAEIGQL STIPPKQRNL DAVKKYVHKK YNLPKEVFSG GFILSKIDGP 420 LSTGNLVLVD TDINSNPTVT FNYFQHPKDL SRCVYGIKTI ERILKTNHFT NFTLNGGGYP 480 MEVVLNMSVT ANINLIPKHT NDSTSMEQFC RDTVVTIWHY HGGCHVGKVV DQQYRVIGVS 540 GLRVIDGSTL FRSPGTNPQA TVMMMGRYMG VKILRRRLGR AAGV* 600 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| TIGR03970 | Rv0697 | 1.0e-24 | 51 | 566 | 574 | + dehydrogenase, Rv0697 family. This model describes a set of dehydrogenases belonging to the glucose-methanol-choline oxidoreductase (GMC oxidoreductase) family. Members of the present family are restricted to Actinobacterial genome contexts containing also members of families TIGR03962 and TIGR03969 (the mycofactocin system), and are proposed to be uniform in function. | ||
| pfam05199 | GMC_oxred_C | 8.0e-26 | 420 | 566 | 152 | + GMC oxidoreductase. This domain found associated with pfam00732. | ||
| TIGR01810 | betA | 5.0e-28 | 51 | 566 | 579 | + choline dehydrogenase. Choline dehydrogenase catalyzes the conversion of exogenously supplied choline into the intermediate glycine betaine aldehyde, as part of a two-step oxidative reaction leading to the formation of osmoprotectant betaine. This enzymatic system can be found in both gram-positive and gram-negative bacteria. As in Escherichia coli , Staphylococcus xylosus , and Sinorhizobium meliloti, this enzyme is found associated in a transciptionally co-induced gene cluster with betaine aldehyde dehydrogenase, the second catalytic enzyme in this reaction. Other gram-positive organisms have been shown to employ a different enzymatic system, utlizing a soluable choline oxidase or type III alcohol dehydrogenase instead of choline dehydrogenase. This enzyme is a member of the GMC oxidoreductase family (pfam00732 and pfam05199), sharing a common evoluntionary origin and enzymatic reaction with alcohol dehydrogenase. Outgrouping from this model, Caulobacter crescentus shares sequence homology with choline dehydrogenase, yet other genes participating in this enzymatic reaction have not currently been identified [Cellular processes, Adaptations to atypical conditions]. | ||
| COG2303 | BetA | 8.0e-39 | 50 | 567 | 588 | + Choline dehydrogenase and related flavoproteins [Amino acid transport and metabolism] | ||
| PLN02785 | PLN02785 | 0 | 5 | 573 | 579 | + Protein HOTHEAD | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0003824 | catalytic activity |
| GO:0005488 | binding |
| GO:0005576 | extracellular region |
| GO:0006629 | lipid metabolic process |
| GO:0007267 | cell-cell signaling |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | EAZ08804.1 | 0 | 1 | 584 | 1 | 585 | hypothetical protein OsI_31066 [Oryza sativa Indica Group] |
| RefSeq | NP_001061757.1 | 0 | 1 | 584 | 1 | 584 | Os08g0401500 [Oryza sativa (japonica cultivar-group)] |
| RefSeq | NP_001062996.1 | 0 | 1 | 584 | 1 | 585 | Os09g0363900 [Oryza sativa (japonica cultivar-group)] |
| RefSeq | NP_001147913.1 | 0 | 1 | 584 | 1 | 580 | protein HOTHEAD [Zea mays] |
| RefSeq | XP_002445466.1 | 0 | 1 | 584 | 1 | 584 | hypothetical protein SORBIDRAFT_07g019920 [Sorghum bicolor] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 1ju2_B | 0 | 49 | 577 | 26 | 517 | A Chain A, Crystal Structure Of The Hydroxynitrile Lyase From Almond |
| PDB | 1ju2_A | 0 | 49 | 577 | 26 | 517 | A Chain A, Crystal Structure Of The Hydroxynitrile Lyase From Almond |
| PDB | 3gdp_B | 0 | 49 | 577 | 26 | 517 | A Chain A, Crystal Structure Of The Hydroxynitrile Lyase From Almond |
| PDB | 3gdp_A | 0 | 49 | 577 | 26 | 517 | A Chain A, Crystal Structure Of The Hydroxynitrile Lyase From Almond |
| PDB | 3gdn_B | 0 | 49 | 577 | 26 | 517 | A Chain A, Almond Hydroxynitrile Lyase In Complex With Benzaldehyde |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| cutin biosynthesis | RXN-2121 | EC-1.1.1 | 18-hydroxyoleate dehydrogenase |
| cutin biosynthesis | RXN-9802 | EC-1.1.1 | 16-hydroxypalmitate dehydrogenase |
| suberin biosynthesis | RXN-2121 | EC-1.1.1 | 18-hydroxyoleate dehydrogenase |
