Basic Information | |
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Species | Prunus persica |
Cazyme ID | ppa005538m |
Family | GT47 |
Protein Properties | Length: 457 Molecular Weight: 51848.4 Isoelectric Point: 7.8076 |
Chromosome | Chromosome/Scaffold: 4 Start: 5491876 End: 5494810 |
Description | Exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 68 | 380 | 0 |
PVKVYLYDLPKRFTYGVIEHHSLARGGRPDEDVSKLKYPGHQHMGEWYLFKDLLKPEAERFGSPVQKVLDPEEADFFYVPFFSSLSLIVNPARPASGSDK PLYSDEENQVALIEWLEEQVYWKRNNGRDHVIMASDPNALYKVIDKVKNSVLLVCDFGRLKEDQGSLVKDVIVPYSHRINTYSGDISVEDRNTLLFFMGN RFRKEGGKIRDLLFQLLENEEDVIIKHGTQSRESRRAASHGMHTSKFCLNPAGDTPSACRLFDSIVSLCVPVIVSDSIELPFEDVIDYRKIAIFVESNAA LKPEFLVSMLRGI |
Full Sequence |
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Protein Sequence Length: 457 Download |
MARKSSLLKQ SLATIVVVLL IYAFLNTFLT PTTTAKLETA LPSFSSASSI SSDVFASREN 60 QLNFPGKPVK VYLYDLPKRF TYGVIEHHSL ARGGRPDEDV SKLKYPGHQH MGEWYLFKDL 120 LKPEAERFGS PVQKVLDPEE ADFFYVPFFS SLSLIVNPAR PASGSDKPLY SDEENQVALI 180 EWLEEQVYWK RNNGRDHVIM ASDPNALYKV IDKVKNSVLL VCDFGRLKED QGSLVKDVIV 240 PYSHRINTYS GDISVEDRNT LLFFMGNRFR KEGGKIRDLL FQLLENEEDV IIKHGTQSRE 300 SRRAASHGMH TSKFCLNPAG DTPSACRLFD SIVSLCVPVI VSDSIELPFE DVIDYRKIAI 360 FVESNAALKP EFLVSMLRGI TTERILEYQK ELNEVKRYFQ YGVPNGTVNE IWRQVAQKLP 420 FIKLSINRDR RLVKRDLNVR DCSCLCSNQT GIITSL* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 3.0e-76 | 65 | 380 | 327 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
EMBL | CAN68074.1 | 0 | 1 | 456 | 1 | 461 | hypothetical protein [Vitis vinifera] |
RefSeq | NP_850241.1 | 0 | 1 | 456 | 1 | 447 | ARAD1 (ARABINAN DEFICIENT 1); catalytic/ transferase, transferring glycosyl groups [Arabidopsis thaliana] |
RefSeq | XP_002318294.1 | 0 | 73 | 456 | 1 | 382 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002322391.1 | 0 | 1 | 456 | 1 | 457 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002523645.1 | 0 | 1 | 456 | 1 | 452 | catalytic, putative [Ricinus communis] |