Basic Information | |
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Species | Linum usitatissimum |
Cazyme ID | Lus10028924 |
Family | GT47 |
Protein Properties | Length: 473 Molecular Weight: 53887.4 Isoelectric Point: 6.87 |
Chromosome | Chromosome/Scaffold: 540 Start: 888848 End: 890266 |
Description | Exostosin family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 54 | 408 | 0 |
CTNRWIHIRRLPTRFNIDLLANCSVYGDLFYDFCPYLSNHGLGPKTHNRSHSWYRTDPFLLELTFHRRMLEYPCLTPDPNQADAVYLPYYAAIDSLRYLY GPEVNNSMDHGLDLFEFLQENEGWIWGKNYGSDHFLVMARPAWDFSQPPDLDPPVWGTSFLELPEFYNLTALVVESRLWAGQEQAIPYLTSFHPPNLELL NSWINRVKASRRTSLMLFAGGGGVSAQANIRRSIRDECENSSSEAFESNGGWYYYSKVCNIVDCSNGKCGHDPILYMRPMLQSTFCLQPPGDTPTRRSTF DAIIAGCIPVFFEDQSARMQYGWHLPEEEYGEFAVHIQKEDVVNKGLKILDVLMG |
Full Sequence |
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Protein Sequence Length: 473 Download |
MASIRISLLP LLFIFILLSL SFNPAISQES SKSRKERAGS SSDSKAHSSP PPDCTNRWIH 60 IRRLPTRFNI DLLANCSVYG DLFYDFCPYL SNHGLGPKTH NRSHSWYRTD PFLLELTFHR 120 RMLEYPCLTP DPNQADAVYL PYYAAIDSLR YLYGPEVNNS MDHGLDLFEF LQENEGWIWG 180 KNYGSDHFLV MARPAWDFSQ PPDLDPPVWG TSFLELPEFY NLTALVVESR LWAGQEQAIP 240 YLTSFHPPNL ELLNSWINRV KASRRTSLML FAGGGGVSAQ ANIRRSIRDE CENSSSEAFE 300 SNGGWYYYSK VCNIVDCSNG KCGHDPILYM RPMLQSTFCL QPPGDTPTRR STFDAIIAGC 360 IPVFFEDQSA RMQYGWHLPE EEYGEFAVHI QKEDVVNKGL KILDVLMGIP RARVRRMRQK 420 VIELIPKIVY RKHGSSAELR AHKDAFDIAI DGALEMIRSR VKGEDFSGMI MK* 480 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 1.0e-47 | 54 | 397 | 356 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
RefSeq | NP_193989.1 | 0 | 44 | 461 | 27 | 435 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | XP_002267390.1 | 0 | 52 | 462 | 31 | 439 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002304426.1 | 0 | 44 | 461 | 19 | 429 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002329867.1 | 0 | 12 | 466 | 8 | 437 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002529790.1 | 0 | 53 | 463 | 36 | 451 | catalytic, putative [Ricinus communis] |