Basic Information | |
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Species | Arabidopsis lyrata |
Cazyme ID | 915839 |
Family | GT47 |
Protein Properties | Length: 537 Molecular Weight: 61677.7 Isoelectric Point: 9.9402 |
View CDS |
External Links |
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NCBI Taxonomy |
Plaza |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 225 | 487 | 0 |
ERKLKVYVYKEGGKPIFHKPLPRGIYASEGWFMKLMESNKKFVVRDPRKAHLFYIPINHLKEYVDLIAGKYKFWNRTGGADHFIVACHDWGNKLTKKTMK NSVRALCNSNVAQGFRIGTDTALPVTYIRSAESPLEYLGGKTPSKRKILAFFAGSMHGYLRPILVKLWENKEPDMKIVGPMPRDPESKTQYREYMKSSKY CICARGYEVHTPRVVEAIINECVPVIIADNYVPPFFEILNWEEFAVFVEEKEIANLRNILLSI |
Full Sequence |
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Protein Sequence Length: 537 Download |
MRIITRLERF HHSDIRRLLS GIIVTVGFVV LLVQCFGIPC PKTFCLSPVT VSVIESTNSN 60 VTQVSVMNYI NLSDIDNVDE EFEEGNKKKD LDGENDVVIS KEKVEINVSV IARANISLRK 120 PIDSSESDPN LVMVRVKDSR NGNVLSMRKN ERGAAISISQ MNSLLIQSLS SFKSPKPRWS 180 SARDSEMLSA RFEIEKASVV HEFLGLNASV YRNISKFLRS YDLMERKLKV YVYKEGGKPI 240 FHKPLPRGIY ASEGWFMKLM ESNKKFVVRD PRKAHLFYIP INHLKEYVDL IAGKYKFWNR 300 TGGADHFIVA CHDWGNKLTK KTMKNSVRAL CNSNVAQGFR IGTDTALPVT YIRSAESPLE 360 YLGGKTPSKR KILAFFAGSM HGYLRPILVK LWENKEPDMK IVGPMPRDPE SKTQYREYMK 420 SSKYCICARG YEVHTPRVVE AIINECVPVI IADNYVPPFF EILNWEEFAV FVEEKEIANL 480 RNILLSISEE RYIVMQARVK AVQQHFLWHK KPVKFDLFHM ILHSIWHSRV YKVKTR* 540 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 1.0e-61 | 224 | 487 | 297 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
DDBJ | BAB08970.1 | 0 | 1 | 536 | 1 | 559 | unnamed protein product [Arabidopsis thaliana] |
EMBL | CAN76867.1 | 0 | 157 | 534 | 265 | 711 | hypothetical protein [Vitis vinifera] |
EMBL | CBI28021.1 | 0 | 157 | 536 | 265 | 665 | unnamed protein product [Vitis vinifera] |
RefSeq | NP_198516.1 | 0 | 1 | 512 | 1 | 544 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | XP_002280595.1 | 0 | 157 | 536 | 263 | 663 | PREDICTED: hypothetical protein [Vitis vinifera] |