Basic Information | |
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Species | Fragaria vesca |
Cazyme ID | mrna22764.1-v1.0-hybrid |
Family | GT47 |
Protein Properties | Length: 406 Molecular Weight: 47116.8 Isoelectric Point: 9.3123 |
Chromosome | Chromosome/Scaffold: 4 Start: 20414436 End: 20415736 |
Description | Exostosin family protein |
View CDS |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 77 | 356 | 0 |
TFKIYVYPTNSSDFAQIFDPHPNPFDPKLGNYFSEHMFKLSLLQSSFITSNPEEAHLYFLPFSVNLLRNDPRVHSEEAISDFVAHYTDGISQEFPFWNAS MGLDHFYACCHSVCREAMSKHNDLHNNAIQLTCSSSYFQRFYIAHKDVSMPQVWPRPPQLTLNPPKSRDKLVFFAGRVQNSNVRQQLVDLWGNDTRMDIY SENPGYPYEEGFKRSKYCLHVKGYEVNTARVSDAIHYGCVPVIMSNYYELPFANVLNWTTFSVIINHNEPASLKKTLLSI |
Full Sequence |
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Protein Sequence Length: 406 Download |
MNALFLYLKK RPKLKQWVFI TIVFLAASSF LWVATSLLQN SHYTSNLGLS APSSLSDSTP 60 YHNFKLFSAD FKDMIQTFKI YVYPTNSSDF AQIFDPHPNP FDPKLGNYFS EHMFKLSLLQ 120 SSFITSNPEE AHLYFLPFSV NLLRNDPRVH SEEAISDFVA HYTDGISQEF PFWNASMGLD 180 HFYACCHSVC REAMSKHNDL HNNAIQLTCS SSYFQRFYIA HKDVSMPQVW PRPPQLTLNP 240 PKSRDKLVFF AGRVQNSNVR QQLVDLWGND TRMDIYSENP GYPYEEGFKR SKYCLHVKGY 300 EVNTARVSDA IHYGCVPVIM SNYYELPFAN VLNWTTFSVI INHNEPASLK KTLLSITKKS 360 YLKMYRNLLA VRRHFIWHKT PKGYDSFHMT AYQLWLKRGS QRPSF* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 4.0e-52 | 78 | 347 | 285 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |