| Basic Information | |
|---|---|
| Species | Oryza sativa |
| Cazyme ID | LOC_Os04g01930.1 |
| Family | GT47 |
| Protein Properties | Length: 442 Molecular Weight: 49439.8 Isoelectric Point: 9.1988 |
| Chromosome | Chromosome/Scaffold: 4 Start: 585941 End: 587523 |
| Description | Exostosin family protein |
| View CDS | |
| External Links |
|---|
| NCBI Taxonomy |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 101 | 392 | 0 |
| ERRFKVYVYEEGEPPILHEGPCKNIYTIEGSFIEQLELMSPSDAGGGVRTWDPTRAHAFFLPFSVSQMVKFVYRPPSQDRAPLRAIVADYVRVVAARHPF WNRSAGADHFMLSCHDWGPYASRGQPELYTNAIRALCNANTSEGFRPGKDVSVPEINLYDGDMPRELLAPAPGLESRPLLAFFAGGRHGHVRDLLLRHWK GRDAATFPVYEYDLPAAGDYYSFMRRARFCLCPSGHEVASPRVVEAIQAECVPVVIADGYALPFADVLRWEAFSVAVAVGDIPRLRERLERI | |||
| Full Sequence |
|---|
| Protein Sequence Length: 442 Download |
| MAPGGAPARS FVVVVLAVIA LSAIVAVAGT KKALSTVDVE EELDAARAAI RRAARQHRRG 60 GGGDVGSANW LRFYGGEADY DLLSRVYRNP AAFYRSYVEM ERRFKVYVYE EGEPPILHEG 120 PCKNIYTIEG SFIEQLELMS PSDAGGGVRT WDPTRAHAFF LPFSVSQMVK FVYRPPSQDR 180 APLRAIVADY VRVVAARHPF WNRSAGADHF MLSCHDWGPY ASRGQPELYT NAIRALCNAN 240 TSEGFRPGKD VSVPEINLYD GDMPRELLAP APGLESRPLL AFFAGGRHGH VRDLLLRHWK 300 GRDAATFPVY EYDLPAAGDY YSFMRRARFC LCPSGHEVAS PRVVEAIQAE CVPVVIADGY 360 ALPFADVLRW EAFSVAVAVG DIPRLRERLE RIPAAEVERL RRGVRLVKRH LMLQQPPRRL 420 DMFNMILHSV WLRGLNLRLH R* 480 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 1.0e-65 | 100 | 392 | 310 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0003824 | catalytic activity |
| GO:0005623 | cell |
| GO:0008152 | metabolic process |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| DDBJ | BAD44815.1 | 0 | 60 | 440 | 91 | 512 | putative pectin-glucuronyltransferase [Oryza sativa Japonica Group] |
| EMBL | CAH67778.1 | 0 | 1 | 441 | 1 | 441 | H0201G08.5 [Oryza sativa (indica cultivar-group)] |
| GenBank | EEC80122.1 | 0 | 60 | 440 | 91 | 543 | hypothetical protein OsI_21883 [Oryza sativa Indica Group] |
| RefSeq | NP_001052025.1 | 0 | 1 | 441 | 1 | 441 | Os04g0109900 [Oryza sativa (japonica cultivar-group)] |
| RefSeq | XP_002437936.1 | 0 | 95 | 431 | 52 | 402 | hypothetical protein SORBIDRAFT_10g005120 [Sorghum bicolor] |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| xylogalacturonan biosynthesis | RXN-9589 | EC-2.4.2.41 | xylogalacturonan β-1,3-xylosyltransferase |
