| Basic Information | |
|---|---|
| Species | Brassica rapa |
| Cazyme ID | Bra028104 |
| Family | GT47 |
| Protein Properties | Length: 542 Molecular Weight: 61920.7 Isoelectric Point: 9.9463 |
| Chromosome | Chromosome/Scaffold: 04 Start: 5767024 End: 5768915 |
| Description | Exostosin family protein |
| View CDS | |
| External Links |
|---|
| NCBI Taxonomy |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 207 | 489 | 0 |
| ERKLRVYVYKEGKKPIFHRPMPRGIYASEGWFMKLMESNKKFLVKDPRKAHLFYIPVSIKALRTSLGLDFQTPKGLADHLKEYVDLIAAKYKFWNRTAGA DHFLVACHDWGNKLTKKHMSNSVRALCNSNVAQGFRIGIDTALPVTYIRSAESPIEYRGGKTPSERKILAFFAGSMHGYLRPILVQLWENKSPDMKIFGP MPRDPQGKKQYREYMKSSRYCICARGYEVHTPRVVEAIINECVPVIIADNYVPPFFEVLNWEEFAVFVEEKDIQNLRNILVSI | |||
| Full Sequence |
|---|
| Protein Sequence Length: 542 Download |
| MRILTRLERF DIRRLLSGII VTVGLVVLLV LCFGIPCRNS FCLSPVNVSG IVANSNEVVS 60 VVKTEINLSS DDDDDEYEEE TRNNGSSREN VKVELNVSIN SSPNVSLGKP EMAVEGSVLV 120 RSNVLPILKR QKQVAATDSI SQMNSLLIRS LSSSHSPKPR WSSARDSEML SAKFEIENAS 180 VVHESPGLDA SVYRNISKFL RSYDLMERKL RVYVYKEGKK PIFHRPMPRG IYASEGWFMK 240 LMESNKKFLV KDPRKAHLFY IPVSIKALRT SLGLDFQTPK GLADHLKEYV DLIAAKYKFW 300 NRTAGADHFL VACHDWGNKL TKKHMSNSVR ALCNSNVAQG FRIGIDTALP VTYIRSAESP 360 IEYRGGKTPS ERKILAFFAG SMHGYLRPIL VQLWENKSPD MKIFGPMPRD PQGKKQYREY 420 MKSSRYCICA RGYEVHTPRV VEAIINECVP VIIADNYVPP FFEVLNWEEF AVFVEEKDIQ 480 NLRNILVSIP EERYIGMQAR VKTVQQHFLW HKKPVKFDLF HMILHSVWHS RLNRVKTKSR 540 H* 600 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 3.0e-66 | 206 | 489 | 304 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| DDBJ | BAB08970.1 | 0 | 1 | 538 | 1 | 559 | unnamed protein product [Arabidopsis thaliana] |
| EMBL | CBI28021.1 | 0 | 128 | 538 | 255 | 665 | unnamed protein product [Vitis vinifera] |
| RefSeq | NP_198516.1 | 0 | 1 | 514 | 1 | 544 | exostosin family protein [Arabidopsis thaliana] |
| RefSeq | XP_002280595.1 | 0 | 128 | 538 | 253 | 663 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002281263.1 | 0 | 121 | 541 | 250 | 672 | PREDICTED: hypothetical protein [Vitis vinifera] |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| xylogalacturonan biosynthesis | RXN-9589 | EC-2.4.2.41 | xylogalacturonan β-1,3-xylosyltransferase |
