Basic Information | |
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Species | Fragaria vesca |
Cazyme ID | mrna16788.1-v1.0-hybrid |
Family | GT47 |
Protein Properties | Length: 720 Molecular Weight: 83333.9 Isoelectric Point: 8.9082 |
Chromosome | Chromosome/Scaffold: 6 Start: 1360277 End: 1364638 |
Description | Exostosin family protein |
View CDS |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 3 | 285 | 0 |
KTFKVWAYREGEVPMVHDGPTTYLYSIEGQFIFEMESGPSPFMAKHPDEAHAFFLPLSVSKITDFLFRPHHETFFHRLDRVFTDYIYVVQEKYPYWNRSD GADHFMVSCHDWASIIQRDDPKPYKNLIKVLCNANISEGFKPTRDCSLPEYNLKAYHLGPPRFGLPPGKRTVLAFFAGAAHGDIRSILFEHWKEKDDEVR VYEKLPDNINYHKIMGQTKFCLCPSGSEVASPRVVEAMNAGCVPVLISDSYAIPFADVLNWNKFSIQIPPKNISEIKTILKAV | |||
GT47 | 386 | 670 | 0 |
KRFKIWAYKEGELPMFHNGPMSYIYSIEGQFMDELDSSGKSPFLARHLHEAHSFFVPVSVKRIADFLYDRPKPYSFHGRLVRIVTDYINVVARKYPYWNR SEGADHFMVSCHDWAPEIINDDLKFYKNFIRVLCNANISEGFQPGRDVSLPEYNLASGTLGPSRLDSHPDERPILAFFAGGAHGDIRKFLFEHWRDKDEE IQVHEYLPKGQNYHQIMGQTKFCLCPSGTEVASPRVVEAMYAGCVPVLISDYYALPFADVLDWSKFTIEIPPKRIPEIKTILKAV |
Full Sequence |
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Protein Sequence Length: 720 Download |
MVKTFKVWAY REGEVPMVHD GPTTYLYSIE GQFIFEMESG PSPFMAKHPD EAHAFFLPLS 60 VSKITDFLFR PHHETFFHRL DRVFTDYIYV VQEKYPYWNR SDGADHFMVS CHDWASIIQR 120 DDPKPYKNLI KVLCNANISE GFKPTRDCSL PEYNLKAYHL GPPRFGLPPG KRTVLAFFAG 180 AAHGDIRSIL FEHWKEKDDE VRVYEKLPDN INYHKIMGQT KFCLCPSGSE VASPRVVEAM 240 NAGCVPVLIS DSYAIPFADV LNWNKFSIQI PPKNISEIKT ILKAVPHKRY LKLQKRVLQV 300 RRHFELNRPA KPFDVFHMPQ PPPLPSPPTS IVADHVKKRS NTNKIEEQLA RARAAIHKAV 360 LTKNYTSDRQ EIYIPRGSVS HIEMVKRFKI WAYKEGELPM FHNGPMSYIY SIEGQFMDEL 420 DSSGKSPFLA RHLHEAHSFF VPVSVKRIAD FLYDRPKPYS FHGRLVRIVT DYINVVARKY 480 PYWNRSEGAD HFMVSCHDWA PEIINDDLKF YKNFIRVLCN ANISEGFQPG RDVSLPEYNL 540 ASGTLGPSRL DSHPDERPIL AFFAGGAHGD IRKFLFEHWR DKDEEIQVHE YLPKGQNYHQ 600 IMGQTKFCLC PSGTEVASPR VVEAMYAGCV PVLISDYYAL PFADVLDWSK FTIEIPPKRI 660 PEIKTILKAV SHTEYLKLQK RVMQVRRHFE LNRPAQPFDV FHMVLHSIWL RRLNIRLPD* 720 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 3.0e-47 | 384 | 651 | 286 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
pfam03016 | Exostosin | 9.0e-54 | 5 | 285 | 301 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Sequence Alignments (This image is cropped. Click for full image.) |
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